TRIC - Therapeutic ROS and Immunity in Cancer

International meeting

online on July 15-16, 2021

​About

 

TRIC is a joint international meeting of the Excellence Programs ONKOTHER-H (Rostock/Greifswald, Germany) and the ZIK plasmatis (with its FiRBaM/YPWS plasma workshop series; INP, Germany).

With regular participation being online, the meeting will take place online on July 15-16, 2021, at the Alfried Krupp Wissenschaftskolleg Greifswald (Germany) and focuses on Plasma Medicine and novel routes in oncology.

With over 30 participants from 12 nations joining 4 Sessions: ​1. Plasma, Cancer, Immunity; 2. Plasma Cancer Combination Therapies; 3. Plasma Risk Assessment and Clinical Safety; 4. Plasma mechanisms and treated liquids in cancer,

Thursday, July 15th 2021
Session 1: Plasma, Cancer, Immunity
Chair: Sander Bekeschus


09.00-09.05

Dr. Christian Suhm

Alfried Krupp Science Kolleg Greifswald

A warm welcome from the host

09.05-09.10

Sander Bekeschus & Lars Boeckmann

A warm welcome from the LOC

09.10-09.40

Sander Bekeschus

ZIK plasmatis, Leibniz Institute for Plasma Science and Technology (INP Greifswald), Germany

Challenges and opportunities of gas plasma technology in oncology and immunology

09.40-10.00

Jinthe van Loenhout

Center for Oncological Research (CORE), Antwerp University Medical Center, Belgium

Investigation of the mechanistic and immunogenic response of auranofin combined with cold atmospheric plasma in glioblastoma

 

10.00-10.20

Hager Mohamed

Institute for Molecular Medicine and Infectious Disease, Drexel University, Philadelphia, USA

Modulation of markers associated with immunogenicity in a model of latent HIV-1 infection using non-thermal plasma

 

10.20-10.40

Ramona Clemen

ZIK plasmatis, Leibniz Institute for Plasma Science and Technology (INP Greifswald), Germany

Gas plasma-medicated oxidative modifications in immunobiology and cancer treatment

 

10.40-11.00

Co Fee (Institute for Hot Caffeine Supply)

coffee break

 

11.00-11.20

Sergej Tomic

Institute for the Application of Nuclear Energy, University of Belgrade, Serbia

Application of plasma activated medium in dendritic cell-based cancer vaccines

 

11.20-11.40

Guojun Chen

Department of Bioengineering and the Rosalind & Morris Goodman Cancer Research Centre, University of California, USA

Transdermal cold atmospheric plasma-mediated immune checkpoint blockade therapy

11.40-12.00

Rashida Ginwala

Institute for Molecular Medicine and Infectious Disease, Drexel University, Philadelphia, USA

Broadening the MHC class 1 epitope repertoire with non-thermal plasma to confer protective immunity against adult T-cell leukemia

 

12.00-12.20

Barbora Smolkova

Institute of Physics of the Czech Academy of Sciences (Prague), Czech Republic

Non-thermal plasma-guided modulation of immune cells: challenges and perspectives

 

12.20-13.30

En Joy (Institute for Carbohydrate Uptake)

lunch break

Thursday, July 15th 2021
Session 2: Plasma cancer combination therapies
Chair: Oleg Lunov


13.30-14.10
Oleg Lunov

Institute of Physics of the
Czech Academy of Sciences (Prague),Czech Republic
Non-thermal plasma and laser irradiation as cues that bias redox balance in cells

14.10-14.30
Franziska Wendt

Institute for Pharmacology and Toxicology, Rostock University Medical Center, Germany
Investigation of small molecules in combination with cold atmospheric plasma as innovative
therapies for the treatment of melanoma und squamous cell carcinoma

 

14.30-14.50
Audrey Glory

Montreal Cancer Institute,Canada
SCRIPT: a novel way to improve the local control of breast cancers using plasmas

 

14.50-15.10
Julia Berner

Department of Oral and Maxillofacial Surgery and Plastic Surgery, Greifswald University Medical Center,
Germany
Adaptive responses of head and neck cancer cells upon repeated exposure to gas plasma over 10 weeks in vitro?

 

15.10-15.30
Andreas Sonnen

Department of Pathology, Utrecht University Medical Center, Germany
Patient cancer organoids as model systems to study treatment response to cold atmospheric
plasma application

 

15.30-16.00
Co Fee (Institute for Hot Caffeine Supply)

coffee break

 

16.00-16.20
Thoralf Bernhardt

Clinic and Policlinic for Dermatology and Venereology, Rostock University Medical Center, Germany
Assessment of Cold Atmospheric Pressure Plasma as Innovative Therapy for Treatment of Radiation Dermatitis using a Mouse Model

 

16.20-16.40
Janith Wanigasekara

BioPlasma Research Group, Technological University Dublin, Ireland
Comparison of 2D and 3D human glioblastoma multiforme cell culture models for cold atmospheric plasma induced cytotoxicity


16.40-17.00
Sanjeev Sagwal

ZIK plasmatis, Leibniz Institute for Plasma Science and Technology (INP Greifswald), Germany
Combination therapy with cold physical plasma and novel molecules in skin cancer in vitro

 

17.00-17.20
Beatriz Lopes

Environmental Sustainability and Health Institute,Technological University Dublin, Ireland
Plasma-activated water and oncology drugs: a possible combinatory effect?

 

17.20-17.40
Anna Frey

Institute of Chemistry, Rostock University, Germany
Synthesis of small molecules for skin cancer treatment with plasma- and non-plasma application


17.40

Sander Bekeschus and Lars Boeckmann

Closing remarks

 

Friday, July 16th 2021
Session 3: Plasma risk assessment and clinical safety
Chair: Lars Boeckmann


09.00-09.40
Lars Boeckmann

Clinic and Policlinic for Dermatology and Venereology, Rostock University Medical Center, Germany
Clinical studies in plasma medicine and safety considerations

 

09.40-10.00
Mirijam Schäfer

Clinic and Policlinic for Dermatology and Venereology, Rostock University Medical Center, Germany
DNA toxicity and mutagenicity of cold atmospheric pressure plasma and small molecules in skin cancer treatment

 

10.00-10.20
Elisa Kwiatek-Scholz

Department of Oral and Maxillofacial Surgery and Plastic Surgery, Greifswald University Medical
Center, Germany
Scientists reflect on animal testing – guideline interviews with following qualitative content analysis

 

10.20-10.40
Katja Evert

Institute of Pathology, Regensburg University Medical Center, Germany
12-months repeated exposure of the oral mucosa with gas plasma is not carcinogenic in mice

 

10.40-11.00
Co Fee (Institute for Hot Caffeine Supply)

coffee break

 

11.00-11.20
Marcel Kordt

Rudolf-Zenker-Institute of Experimental Surgery, Rostock University Medical Center, Germany
Evaluation of the angiogenesis modulating effect of cold atmospheric pressure plasma on skin cancer in vivo

 

11.20-11.40
Endre Szili

University of South Australia, Australia
DNA damage induced by plasma: opportunities in cancer therapy and safety implications

 

11.40-12.00
Christian Seebauer

Department of Oral and Maxillofacial Surgery and Plastic Surgery, Greifswald University Medical Center, Germany
Plasma treatment of intraoral mucosal disorders: evaluation of safety

 

12.00-12.20
Daniela Boehm

Environmental Sustainability and Health Institute,Technological University Dublin, Ireland
Safety and cellular response pathways to reactive species in plasma-activated liquids

 

12.20-13.30
En Joy (Institute for Carbohydrate Uptake)

lunch break

 

Friday, July 16th 2021
Session 4: Plasma mechanisms and treated liquids in cancer
Chair: Pierre-Marie Girard

13.30-14.10
Kyriakos Sklias and Pierre-Marie Girard
CNRS Orsay, France 
On the selectivity of plasma treatment in vitro due to short- and long-lived RONS

 

14.10-14.30
Dayun Yan

George Washington University, USA
Physical effects of CAP on cancer cells

 

14.30-14.50
Romolo Laurita

Department of Industrial Engineering, Bologna University, Italy
On the use of Plasma Activated Liquids for the treatment of cancer cells

 

14.50-15.10
Miguel Mateu-Sanz

Technical University of Catalonia (UPC), Spain
Cold plasma-treated ringer’s saline for the treatment of osteosarcoma

 

15.10-15.30
Thai-Hoa Chung

Gustave Roussy Institute Paris, France
Cell Electropermeabilisation Enhancement by Non-Thermal-Plasma-Treated PBS

 

15.30-16.00
Co Fee (Institute for Hot Caffeine Supply)

coffee break

 

16.00-16.20
Lea Miebach

Clinic for General, Visceral, Thoracic, and Vascular Surgery, Greifswald University Medical Center,
Germany
Efficacy and immunogenicity of plasmaoxidized saline against peritoneal carcinomatosis in vitro and in vivo and compared to H2O2-matched controls

 

16.20-16.40
Andressa Carvalho

Technological University Dublin, Ireland
Pin Electrode Reactor: A novel cold atmospheric plasma device and its potential in glioblastoma treatment

 

16.40-17.00
Yun-Chien Cheng

National Chiao Tung University, Taiwan
The Effects of Atmospheric-pressure Cold plasma Generated Short and Long-life Species
and Electric Fields on Skin Cancer Cells


17.00-17.20
Anne-Christin Waldner

Rostock University Medical Center, Germany
Selective inhibition of adhesion of dermal tumor cells by plasma-activated medium

 

17.20-17.40
Valeria Veronico

Department of Chemistry, University of Bari, Italy
Tailoring the chemistry of plasma treated water solutions to selectively attack cancer cells

 

17.40

Sander Bekeschus and Lars Boeckmann

Closing remarks

 Local Organizing Committee:

Dr. Sander Bekeschus

Ramona Clemen 

ZIK plasmatis, Leibniz Institute for Plasma Science and Technology (INP Greifswald), Germany

Prof. Dr. Steffen Emmert
Dr. Lars Boeckmann

Dr. Tobias Fischer 

 

Clinic for Dermatology and Venereology

University Medical Center Rostock

Strempelstrasse 13

18057 Rostock

Germany

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